首页> 外国专利> 1,2- PYRIDAZINE, 1,6- PYRIDAZINE OR PYRIMIDINE - BENZAMIDE DERIVATIVES AS GPBAR1 MODULATORS

1,2- PYRIDAZINE, 1,6- PYRIDAZINE OR PYRIMIDINE - BENZAMIDE DERIVATIVES AS GPBAR1 MODULATORS

机译:1,2-吡嗪,1,6-吡嗪或嘧啶-苯甲酰胺衍生物作为GPBAR1调节剂

摘要

This invention relates to novel 1,2-pyridazines, 1,6-pyridazines or pyrimidines of the formula wherein B1 to B3 and R1 to R7 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and may therefore be useful as medicaments for the treatment of diseases such as type II diabetes.
机译:本发明涉及下式的新的1,2-哒嗪,1,6-哒嗪或嘧啶,其中B1-B3和R1-R7如说明书和权利要求中所定义,及其药学上可接受的盐。这些化合物是GPBAR1激动剂,因此可用作治疗II型糖尿病等疾病的药物。

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