NOVEL INHIBITORS OF THE NEW DELHI METALLO BETA LACTAMASE (NDM-1)

摘要

Novel inhibitors of the New Delhi Metallo-B-lactamase (NDM-1) and variants thereof are provided. In certain embodiments, the inhibitors are thiourea derivatives. Methods of using the inhibitors for inhibition of NDM-1 and bacteria expressing NDM-1 are also provided.