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IN VITRO METHOD FOR PREDICTING DISEASE OUTCOME IN STAGE II COLORECTAL CANCER

机译:预测II期大肠癌疾病结局的体外方法

摘要

The present invention relates to a method for determining the likelihood of disease outcome of a patient diagnosed with microsatellite stable, stage II colorectal cancer. More in particular, the present invention relates to a method for determining the prognosis of a patient diagnosed with microsatellite stable, stage II colorectal cancer wherein the CpG island methylation status of the promoter of the CHFR gene is determined and wherein methylation of the promoter is indicative of a poor prognosis.
机译:本发明涉及一种确定诊断为微卫星稳定的II期结直肠癌的患者的疾病结果的可能性的方法。更具体地,本发明涉及一种确定诊断为微卫星稳定的II期结直肠癌的患者的预后的方法,其中确定CHFR基因的启动子的CpG岛甲基化状态,并且其中该启动子的甲基化是指示性的预后不良。

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