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SHEET AND LIQUID COMBINATION SYSTEMS FOR DERMAL DELIVERY OF LIDOCAINE, DICLOFENAC, AND OTHER DRUGS
SHEET AND LIQUID COMBINATION SYSTEMS FOR DERMAL DELIVERY OF LIDOCAINE, DICLOFENAC, AND OTHER DRUGS
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机译:利多卡因,双氯芬酸和其他药物经皮递送的片材和液体组合系统
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摘要
A system for dermal delivery of lidocaine, bupivacaine, diclofenac, or ketoprofen is provided which comprises at least two components, for example, a sheet of a solid and flexible material, and a vehicle liquid comprising a solvent and optionally other ingredients. A drug, selected from group consisting of lidocaine, bupivacaine, diclofenac, and ketoprofen, can be impregnated in the sheet or contained in the vehicle liquid. These two components can be stored separately and joined either shortly before or at the time of application. To use the system, the vehicle liquid may be applied either on the target skin area or on the sheet, and the sheet may then be applied on the target skin area so that the vehicle liquid is positioned between the sheet and the skin and brought into contact with the ingredients impregnated in the sheet.
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