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NEW BIOMARKERS FOR THE DIAGNOSIS AND/OR PROGNOSIS OF CLEAR CELL RENAL CELL CARCINOMA

机译:诊断和/或预测透明细胞肾细胞癌的新生物标志物

摘要

The present invention provides an in vitro method for the diagnosis and/or prognosis of clear cell Renal Cell Carcinoma in a subject suspected of suffering it, in which method the presence and levels of a phosphorylated form of the protein Signal transducer and activator of transcription 3 (STAT3) are determined. Said determination is performed in any isolated sample, in particular in a biopsy of a tumor. The invention relates also to the use of means for detecting said phosphorylated form to be applied in the method for the diagnosis and/or prognosis of clear cell Renal Cell Carcinoma.
机译:本发明提供了在怀疑患有透明细胞肾细胞癌的受试者中诊断和/或预后透明细胞肾细胞癌的体外方法,该方法中蛋白质信号转导子和转录激活子3的磷酸化形式的存在和水平。 (STAT3)被确定。所述确定在任何分离的样品中进行,特别是在肿瘤的活检中进行。本发明还涉及用于检测所述磷酸化形式的装置在诊断和/或预后透明细胞肾细胞癌的方法中的用途。

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