An implantable neurostimulator-implemented method of vagus nerve stimulation is provided. An implantable neurostimulator, including a pulse generator, is configured to deliver electrical therapeutic stimulation in a manner that results in creation and propagation (in both afferent and efferent directions) of action potentials within neuronal fibers comprising the cervical vagus nerve of a patient. Operating modes of the pulse generator are stored. Maintenance, restorative and enhanced doses of the electrical therapeutic stimulation are parametrically defined and delivered to the vagus nerve via the pulse generator. The patient's physiological state is monitored via at least one sensor.
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