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SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES WITH ULTRA-THIN POLYMER LAYERS, THE METHOD OF THEIR PREPARATION AND APPLICATION
SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES WITH ULTRA-THIN POLYMER LAYERS, THE METHOD OF THEIR PREPARATION AND APPLICATION
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机译:具有超薄聚合物层的超顺磁性氧化铁纳米粒子,其制备方法和应用
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摘要
This invention relates to superparamagnetic iron oxide nanoparticles with ultra-thin polymer layers characterized in that they consist of superparamagnetic iron oxide cores co- precipitated with polycation, and a hydrophilic coating consisting of at least one ultra-thin layer of polyelectrolyte. The invention also provides a method for producing superparamagnetic nanoparticles according to the invention, and the use of superparamagnetic nanoparticles according to the invention as a contrast agent in magnetic resonance imaging and/or fluorescence imaging and/or fluorescence microscopy.
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