首页> 外国专利> Method of Providing Useful Data for the Diagnosis and Therapy of the Diseases Induced by House Dust Mite Comprising Analysis of Expression Level of Beta-Catenin Protein

Method of Providing Useful Data for the Diagnosis and Therapy of the Diseases Induced by House Dust Mite Comprising Analysis of Expression Level of Beta-Catenin Protein

机译:为屋尘螨所致疾病的诊断和治疗提供有用数据的方法,包括β-连环蛋白的表达水平分析

摘要

The present invention relates to a method for providing useful information for diagnosis and therapy of house dust mite-induced diseases by comprising a step of measuring expression levels of regulator protein constituting a WNT/beta-catenin pathway, and a kit for diagnosis of dust mite-induced diseases, comprising an antibody binding to the regulator protein. Further, the present invention relates to a method for screening a candidate material for therapy of house dust mite-induced diseases and a composition used in the screening method. The present invention can cheaply and simply provide useful information for diagnosis and therapy of house dust mite-induced diseases by measuring the expression level of regulator protein of the WNT/beta-catenin path, and screen a candidate material for therapy of house dust mite-induced diseases in a manner of high rate and high capacity.
机译:本发明涉及通过包括测量构成WNT /β-连环蛋白途径的调节蛋白的表达水平的步骤来提供用于诊断和治疗屋尘螨诱发的疾病的有用信息的方法以及用于尘螨诊断的试剂盒引起的疾病,包括与调节蛋白结合的抗体。此外,本发明涉及用于筛选用于治疗由屋尘螨引起的疾病的候选材料的方法和用于该筛选方法的组合物。通过测量WNT /β-catenin途径的调节蛋白的表达水平,并筛选用于治疗屋尘螨的候选材料,本发明可以便宜而简单地为屋尘螨诱发的疾病的诊断和治疗提供有用的信息。以高发病率和高发病率的方式诱发疾病。

著录项

  • 公开/公告号KR101462088B1

    专利类型

  • 公开/公告日2014-11-19

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20120058578

  • 发明设计人 윤유식;배성민;이해용;

    申请日2012-05-31

  • 分类号C12Q1/68;G01N33/53;G01N33/15;G01N33/68;

  • 国家 KR

  • 入库时间 2022-08-21 15:01:15

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