EGFR-positive cancer targeted quenched nanoprobe and method for preparing the same

摘要

The present invention relates to epidermal growth factor receptor (EGFR) -positive tumor-targeted, light-extinguishing nanoprobe and a method for producing the same. More specifically, the present invention relates to a skin growth factor (EGF) Growth Factor Receptor (EGFR) - Positive Tumor Targeting Extinction Nanoprobe and a method for its manufacture. The epidermal growth factor receptor (EGFR) -b positive tumor targeted extinction nanoprobe (EGF-NP) according to the present invention is capable of specifically detecting epidermal growth factor receptor-positive tumors and is therefore capable of specifically detecting epidermal growth factor receptor- It is very effective in monitoring treatment effects. In addition, since it has a short imaging time, it is easy to perform repetitive image acquisition easily and is useful for acquiring continuous image data over time. In addition, since EGF-NP according to the present invention disappears in the body after a lapse of a predetermined time, it is also excellent in terms of safety.