ANTITUMOR AGENT FOR UNDIFFERENTIATED GASTRIC CANCER

摘要

The present invention relates to a therapeutic agent represented by the following general formula (I), or a pharmacologically acceptable salt thereof, or a solvate thereof.;The compound of formula (I);The therapeutic agent contains a substance having activity to inhibit the kinase activity of fibroblast growth factor receptor 2 (" FGFR2 "). The therapeutic agent can be used to treat undifferentiated gastric cancer, and can be used to treat a cell overexpressing FGFR2 or a cell expressing mutant FGFR2, or both. The present invention also relates to a pharmaceutical composition containing an FGFR2 inhibitory substance and a therapeutic method using the pharmaceutical composition. The present invention also relates to a method for predicting the effect of an FGFR2 inhibitor on a patient.