COMPOSITION CONTAINING NONPOLAR SOLVENT SOLUBLE EXTRACT OF CURCUMA LONGA L. OR AROMATIC TURMERONE ISOLATED THEREFROM AS ACTIVE INGREDIENT FOR TREATMENT AND PREVENTION OF STRESS-RELATED DISEASE

摘要

The present invention relates to a composition containing a nonpolar solvent soluble extract of Curcuma longa L. or aromatic turmerone isolated therefrom. According to the present invention, a cytotoxicity experiment using the cerebral cortex of an SD rat and a verification experiment of a neuronal damage-preventive effect have been performed on a nonpolar solvent soluble extract of Curcuma longa L. or aromatic turmerone isolated therefrom, wherein the neuronal damage-preventive effect refers to neuronal damage caused by corticosterone that is a stress hormone secreted due to psychological stress in cerebral cortex cells. As results of the experiments, it has been verified that the nonpolar solvent soluble extract of Curcuma longa L. or aromatic turmerone isolated therefrom has a strong neuronal damage-preventive effect. Accordingly, it has been verified that the composition is useful for a pharmaceutical composition or a health food for prevention and treatment of a stress-related disease.;COPYRIGHT KIPO 2015