Composition of Cosmetics and OTC drugs for Acne Skin Containing Micronized Salicylic Acid Using Ecofriendly Density Fluctuation Supercritical Fluid

摘要

It includes process that the present invention relates to the compositions of the supercritical fluid method of particle Salicylic Acid Formulations use environment close friend and quasi- drug and cosmetics for acne skin. The present invention relates to a kind of particle salicylic acids for manufacturing ultra-fine grain to use the supercritical fluid process, includes the following steps: which salicylic acid dissolution generates bigcatkin willow acid particles is made through by spraying mixture solution in organic solvent with supercritical fluid for contact; It removes solution used in the ORGANIC SOLVENT MIXTURES and is passed through supercritical fluid to particle, and application cosmetics and quasi- pharmaceutical composition contain acne skin, whereinThe manufacturing method allows to change the drug of crystallization, by change operation temperature with pressure condition identical or flux salicylic acid, the treatment with supercritical fluid of organic solvent and supercritical carbon dioxide in solution, the effect for being accordingly used in manufacture whose skin preparation of salicylic acid, which will increase, to be converted to by these drug microparticles partial sizes and has accordingly resulted in increased region. ;The 2015 of copyright KIPO submissions