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BIOMARKER FOR PREDICTING AND DIAGNOSING DRUG-INDUCED LIVER INJURY

机译:预测和诊断药物引起的肝损伤的生物标记

摘要

The present invention relates to a biomarker for predicting and diagnosing a drug-induced liver injury. The biomarker of the present invention means genes, which are sensitively reactive to a drug-induced liver injury, selected based on transcriptomics. The biomarker of the present invention may be usefully used in the prediction and diagnosis of a drug-induced liver injury and in particular, may be usefully used in the analysis of the type of the liver injury. In addition, the biomarker of the present invention has the advantage of diagnosing and predicting a toxicity caused by a drug promptly and accurately at an early stage, and may be able to prevent side effects caused by the toxicity caused by a drug at an early stage.
机译:本发明涉及用于预测和诊断药物引起的肝损伤的生物标志物。本发明的生物标志物是指基于转录组学选择的对药物诱发的肝损伤敏感的基因。本发明的生物标志物可用于预测和诊断药物诱导的肝损伤,特别是可用于分析肝损伤的类型。另外,本发明的生物标志物具有在早期迅速且准确地诊断和预测由药物引起的毒性的优点,并且能够在早期预防由药物引起的毒性引起的副作用。 。

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