首页> 外国专利> STEM CELL CULTURE MEDIUM CONTAINING CELL GROWTH FACTORS FROM HUMAN ADIPOSE-DERIVED STEM CELLS AND COSMETIC COMPOSITION FOR ALLEVIATING ATOPIC DERMATITIS

STEM CELL CULTURE MEDIUM CONTAINING CELL GROWTH FACTORS FROM HUMAN ADIPOSE-DERIVED STEM CELLS AND COSMETIC COMPOSITION FOR ALLEVIATING ATOPIC DERMATITIS

机译:包含人类脂肪干细胞和化妆品成分的干细胞培养基,用于缓解原子性皮炎

摘要

The present invention provides a culture medium composition for growing human adipose-derived stem cells, which expresses CD73, CD90, and CD105, but not CD34 and CD45 and contains cell growth factors such as EGF, VEGF, TGF, FGF, and HGF efficiently, and a medical composition containing active ingredients like the same for preventing and treating atopic diseases. The culture medium of stem cells, which expresses positive surface markers of the human adipose-derived stem cells CD73, CD90, and CD105 specifically but not negative surface marker CD34 andCD45, used in the present invention is capable of inhibiting atopic symptoms and reducing an IgE level. The present invention provides a stem cell medium for producing the stem cell culture medium, which specifically contains cell growth factors, and a pharmaceutical composition containing the cell growth factors as active ingredients for preventing or treating atopic dermatitis. In addition, the present invention provides a cosmetic composition containing the stem cell culture medium or a lyophilizate thereof for alleviating or relieving atopic dermatitis.;COPYRIGHT KIPO 2015
机译:本发明提供了用于培养人脂肪来源的干细胞的培养基组合物,其表达CD73,CD90和CD105,但不表达CD34和CD45,并有效地包含细胞生长因子,例如EGF,VEGF,TGF,FGF和HGF,以及含有类似活性成分的药物组合物,用于预防和治疗特应性疾病。在本发明中使用的干细胞培养基能特异性地表达人脂肪干细胞CD73,CD90和CD105的阳性表面标记,但不表达阴性表面标记CD34和CD45,而能够抑制特应性症状并降低IgE水平。本发明提供了用于生产特别包含细胞生长因子的干细胞培养基的干细胞培养基,以及包含所述细胞生长因子作为预防或治疗异位性皮炎的活性成分的药物组合物。另外,本发明提供了包含干细胞培养基或其冻干物的化妆品组合物,用于减轻或缓解特应性皮炎。; COPYRIGHT KIPO 2015

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