DENDRIMER-BASED RETINAL DRUG DELIVERY SYSTEMS WITH FACILE RETINAL PENETRATION PROPERTIES BY ADJUSTING THEIR SURFACE FUNCTIONALITIES

摘要

The present invention relates to the pharmaceutical carriers treated based on dendroid retinal disease can be easily penetrate into chorioretinal aldehyde layer by using intravitreal injection method or the method for eye drops. According to the present invention, the core of the functional group of the pharmaceutical carrier modification terminating functional groups of retinal disease treatment, to raising ocular penetration performance. Therefore, which can effectively pass through outer layer, such as the cornea or sclera of eyes are falling or be injected into the choroid of eyes in order to which the layers,retinal that penetrates into is in glass and glass itself, thus the drug that the retinal disease for becoming useful carrier is treated. ;The 2016 of copyright KIPO submissions