Compositon for maturating dendritic cell comprising Mycobacterium tuberculosis Rv2769c

摘要

The invention maturation inducing composition of the dendritic cell comprising the Rv2769c protein of Mycobacterium tuberculosis as an active ingredient, methods for inducing the maturation process the Rv2769c protein of Mycobacterium tuberculosis in the immature dendritic cell, and immune containing the Rv2769c protein as an active ingredient It relates to a composition for use. The present Rv2769c according to the invention stimulate immature dendritic cells, proinflammatory cytokine TNF-α, IL-6, secretion of IL-1β and the protein surface markers of CD80, expression of CD86, MHC class I, II of the cell promoting differentiation to mature into mature dendritic cells, and an increased, this has the effect of effectively enhancing the body's immune response. ;