METHOD OF SCREENING A SUBSTANCE CAPABLE OF INHIBITING INTERACTION BETWEEN PRP19 AND CLIC PROTEINS AND A COMPOSITION COMPRISING THE SCREENED SUBSTANCE

摘要

The present invention relates to a method for screening a substance which interferes with the interaction between PRP (precursor RNA processing) 19 protein and CLIC (intracellular chloride channel) protein, and a cosmetic composition or a pharmaceutical composition . According to the method of the present invention, substances capable of interfering with the interaction between the PRP19 protein and the CLIC protein can be rapidly and rapidly searched in a small amount, and the substances retrieved by the method of the present invention can inhibit the formation of fat, Can be useful for the treatment and prevention of diseases mediated by the interaction between PRP19 protein and CLIC protein, including obesity.