Methods for cancer diagnosis, anti-cancer drug screening, and test of drug effectiveness on the basis of phoshorylation of Ras at Thr-144 and Thr-148

摘要

Ras invention is a method based cancer diagnostics and cancer screening methods to be about. Ras oncogene is a major one being its abnormality is found in almost all of the cancer, cancer diagnosis and cancer screening method using the Ras has a very important significance can be applied to a variety of cancers. In accordance with the present invention by examining the phosphorylation whether at Thr144 and Thr148 position of Ras may determine the occurrence of various types of cancer at an early stage, by using such a mechanism, screening an anticancer agent having an excellent antitumor effect, or to test the efficacy of anti-cancer agents can. ;