首页> 外国专利> Composition for adhesion or proliferation of dental pulp cells comprising recombinant dentin phosphoprotein

Composition for adhesion or proliferation of dental pulp cells comprising recombinant dentin phosphoprotein

机译:包含重组牙本质磷蛋白的用于牙髓细胞粘附或增殖的组合物

摘要

The present invention relates to a composition for promoting adherence or proliferation of dental pulp cells containing dentin phosphoprotein as an active ingredient, and a method for improving the adhesion or proliferation of dental pulp cells, Or a method of inducing proliferation. By using the recombinant human dentin phosphate protein capable of mass production using the expression vector of the present invention, it is possible to promote the proliferation of the dendritic cells, increase the cell adhesion capacity, and promote the differentiation into the dendritic cells from the dendritic cells Respectively. Therefore, the recombinant human dentin phosphate protein of the present invention is widely used for promoting the proliferation and adhesion of dendritic cells in the fields of tissue engineering materials, dental bone regeneration therapeutic agents and medicament therapeutic agents related to recovery and regeneration of teeth and bone tissues It will be possible.
机译:本发明涉及一种以牙本质磷蛋白为有效成分的促进牙髓细胞的粘附或增殖的组合物,改善牙髓细胞的粘附或增殖的方法或诱导增殖的方法。通过使用能够使用本发明的表达载体大量生产的重组人牙本质磷酸蛋白,可以促进树突状细胞的增殖,提高细胞的粘附能力,并促进从树突状细胞向树突状细胞的分化。细胞分别。因此,本发明的重组人牙本质磷酸蛋白在组织工程材料,牙齿骨再生治疗剂和与牙齿和骨骼的恢复和再生有关的药物治疗剂领域中广泛用于促进树突状细胞的增殖和粘附。组织将是可能的。

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