A method of predicting pre-eclampsia in pregnant women with placental insufficiency

摘要

FIELD: medicine.;SUBSTANCE: blood angiogenic factors sFlt-1 and PIGF are measured in the pregnant women with clinically and laboratory diagnosed placental insufficiency (PI); that is followed by calculating the angiogenic coefficient Ka by formula: Ka=sFlt-1/(PIGF×10), and if Ka makes 250 or more, preeclampsia is predicted in the pregnant woman with PI.;EFFECT: method enables predicting preeclampsia in the pregnant women with PI for the purpose of selecting further therapeutic approach on the basis of the determined coefficient; in the end it enables making a decision on the rate and extent of clinical-laboratory examination involving all the measures conducted at a suspicion on preeclampsia.;4 ex