首页> 外国专利> FOLIC ACID AND RAMIPRIL COMBINATION: CYTO-PROTECTIVE, NEURO-PROTECTIVE AND RETIN-PROTECTIVE OPHTHALMOLOGICAL COMPOSITIONS

FOLIC ACID AND RAMIPRIL COMBINATION: CYTO-PROTECTIVE, NEURO-PROTECTIVE AND RETIN-PROTECTIVE OPHTHALMOLOGICAL COMPOSITIONS

机译:叶酸和RAMIPILIL组合:细胞保护性,神经保护性和视网膜保护性眼科组合物

摘要

1. A composition characterized in that it contains at least two active components selected from an angiotensin converting enzyme inhibitor (ACE inhibitor), folic acid, folate, magnesium, potassium, glucose, amino acids (especially leucine, and in particular acetyleucine), L-arginine , tetrahydrobiopterin (H4B), vitamin B6, vitamin B12, vitamin C, w-3 fatty acids, anti-inflammatory agents, beta-blocking agents, epinephrine, norepinephrine, alpha adrenergic agonist agents, anti-growth factor agents and vascular endothelial (anti-VEGF), their pharmaceutically acceptable salts or derivatives thereof and smesey.2. The composition according to claim 1, which contains: a) a first active component that essentially consists of or consists of ACE inhibitors, and b) a second active component that is selected from folic acid, folate, magnesium, potassium, glucose, amino acids ( especially leucine, and in particular acetyleucine), one of their pharmaceutically acceptable salts, their derivatives and mixtures thereof, and c) optionally, a third active component that is selected from L-arginine, H4B, vitamin B6, vitamin B12, vitamin C, w- 3 fatty acids, anti-inflammatory agents, beta blocking agents, hell enalina, noradrenaline, agents representing alpha-adrenergic agonists, anti-VEGF agents and their smesey.3. The composition according to claim 1 or 2, characterized in that the ACE inhibitor contains essentially consists of or consists of ramipril, ramiprilat, one of their pharmaceutically acceptable salts or any derivative of ramipril or ramiprilat, which can release ramipril or ramiprilat in the animal’s body, to which the indicated active com
机译:1.一种组合物,其特征在于,其包含至少两种选自血管紧张素转化酶抑制剂(ACE抑制剂),叶酸,叶酸,镁,钾,葡萄糖,氨基酸(特别是亮氨酸,特别是乙酰丁氨酸)的活性成分,L -精氨酸,四氢生物蝶呤(H4B),维生素B6,维生素B12,维生素C,w-3脂肪酸,抗炎剂,β受体阻滞剂,肾上腺素,去甲肾上腺素,α肾上腺素能激动剂,抗生长因子剂和血管内皮细胞(抗-VEGF),其药学上可接受的盐或其衍生物和smesey.2。 2.根据权利要求1所述的组合物,其包含:a)基本上由ACE抑制剂组成或由其组成的第一活性组分,以及b)选自叶酸,叶酸,镁,钾,葡萄糖,氨基酸的第二活性组分。 (特别是亮氨酸,特别是乙酰丁氨酸),它们的药学上可接受的盐,它们的衍生物和混合物之一,以及c)任选地,第三活性成分,其选自L-精氨酸,H4B,维生素B6,维生素B12,维生素C ,w-3脂肪酸,抗炎药,β阻滞剂,地狱enalina,去甲肾上腺素,代表α-肾上腺素能激动剂的药物,抗VEGF药物及其药物。3。 3.根据权利要求1或2所述的组合物,其特征在于,所述ACE抑制剂包含基本上由雷米普利,雷米普利拉,其药学上可接受的盐之一或雷米普利或雷米普利拉的任何衍生物组成或组成,所述雷米普利,雷米普利特可以在动物体内释放雷米普利或雷米普利拉。 ,其中指示的活动com

著录项

  • 公开/公告号RU2013125146A

    专利类型

  • 公开/公告日2015-01-10

    原文格式PDF

  • 申请/专利权人 РЕКИК РАУФ (TN);

    申请/专利号RU20130125146

  • 发明设计人 РЕКИК РАУФ (TN);

    申请日2011-05-06

  • 分类号A61K31;

  • 国家 RU

  • 入库时间 2022-08-21 14:57:12

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