ALLOCATED COMPOUNDS FROM TURKMEN OIL AND WAYS OF APPLICATION

摘要

1. A compound having the formula I-0: or a pharmaceutically acceptable salt thereof, selected from a single bond and a double bond; R is selected from CH, CH, F, Cl, Br, CF, O-alkyl and OCF; R is selected from CHC (CH) OH and CH = C (CH); and R is selected from OH and NHCHCH (CH). 2. The compound according to claim 1, selected from: 2-methyl-6-p-tolylhept-2-en-4-ol; 2-methyl-6- (4-methylcyclohexa-1,3-dienyl) hept-2-en- 4-ol; 2-methyl-6-p-tolylheptane-2,4-diol; N-isobutyl-2-methyl-6- (p-tolyl) hept-2-en-4-amine; 4- (isobutylamino) -2-methyl-6-p-tolylheptan-2-ol; 4- (isobutylamino) -2-methyl-6- (4-methylcyclohexa-1,3-dienyl) heptan-2-ol and their pharmaceutically acceptable salts. 3 . A compound having the formula I-1: or a pharmaceutically acceptable salt thereof, selected from a single bond and a double bond; R is selected from CH, CH, F, Cl, Br, CF, O-alkyl and OCF; R is selected from CHC (CH) OH and CH = C (CH); and R is selected from OH and NHCHCH (CH). 4. The compound according to claim 3, selected from: (6S) -2-methyl-6-p-tolylhept-2-en-4-ol; (6S) -2-methyl-6- (4-methylcyclohexa-1,3- dienyl) hept-2-en-4-ol; (6S) -2-methyl-6-p-tolylheptane-2,4-diol; (6S) -N-isobutyl-2-methyl-6- (p-tolyl ) hept-2-en-4-amine; (6S) -4- (isobutylamino) -2-methyl-6-p-tolylheptan-2-ol; (6S) -4- (isobutylamino) -2-methyl-6 - (4-methylcyclohexa-1,3-dienyl) heptan-2-ol and their pharmaceutically acceptable salts. 5. A compound having the formula I-2: or a pharmaceutically acceptable salt thereof, selected from a single bond and a double bond; R is selected from CH, CH, F, Cl, Br, CF, O-alkyl and OCF; R is selected from CHC (CH) OH and CH = C (CH); and R is selected from OH and NHCHCH (CH). 6. The compound according to claim 5, selected from: (4S, 6S) -N-isobutyl-2-methyl-6-p-tolylhept-2-en-4-amine; (4R, 6S) -N-isobutyl-2-methyl -6-p-tolylhept-2-en-4-amine and their pharmaceutically acceptable salts. 7. A pharmaceutical composition containing a therapeutically effective amount of a compound of formula I-0: wherein it is selected from a single bond and a double bond; R is selected from CH, CH, F, Cl, Br, CF, O-alkyl and OCF; R is selected from CHC (CH) OH and C