SIGMA-1 AGONIST OF AFOBAZOL RECEPTORS-A NEW MEDICINAL PREVENTION FOR PREVENTION OF EXCEPTIONAL CARDIAC MORTALITY IN PATIENTS AFFECTING ALCOHOLIC CARDIOMYOPATHY AND METHOD OF ITS MODEL

摘要

1. The use of 5-ethoxy-2- [2- (morpholino) -ethylthio] benzimidazole dihydrochloride - afobazole - as a means for the prevention of sudden cardiac death in alcoholic cardiomyopathy. 2. A method for modeling alcoholic cardiomyopathy, which consists in forced alcoholization of animals with a 10% aqueous solution of ethanol for 13 weeks, the subsequent selection of animals with a high preference for alcohol and continued alcoholization until the end of 6 months from the start of alcoholization.