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PHARMACEUTICAL PRODUCT FOR PREVENTION AND TREATMENT OF PROGRESSING MYOPIDITY

机译:预防和治疗进展性肌病的药物产品

摘要

1. A pharmaceutical preparation for the prevention and treatment of progressive myopia, which is an aqueous solution for instillations, or an eye gel, or an ophthalmic film containing an effective amount of an amine with functional groups in the form of a salt, or as part of a transition metal complex compound, or mixtures thereof. 2. The preparation according to claim 1, characterized in that the concentration of a salt or complex compound of an amine-based transition metal with functional groups in solution is 0.15-7.0 wt.%. 3. The preparation according to claim 1, characterized in that distilled water or an isotonic solution or a mixture thereof is used as the aqueous medium for the solution. The preparation according to claim 3, characterized in that the physiological or balanced physiological solution of BBS and / or aqueous solutions of nonionic compounds, such as glycerin, or sorbitol, or beckons, or propylene glycol, or dextrose, are selected as the isotonic solution. The drug according to claim 1, characterized in that the aqueous solution further comprises a gelling agent. The preparation according to claim 5, characterized in that the gelling agent used is hyaluronic acid, chondroitin sulfate, or polyvinyl alcohol, or methyl cellulose, or hydroxyethyl cellulose, or hydroxypropyl cellulose, or hydroxypropyl guar, or polyethylene glycol-polypropylene glycol-polyethylene glycol cellulose-copolymer, polyethylene glycol cellulose a salt of a crosslinked polyacrylic acid and its copolymers with C10-30 alkyl acrylates, or a mixture thereof. 7. The preparation according to claims 5 and 6, characterized in that the content of the gelling agent in the aqueous solution is 0.1-25.0 wt.%. 8. A drug
机译:1.用于预防和治疗进行性近视的药物制剂,其是滴剂水溶液,眼药水或含有有效量的具有盐形式的官能团的胺的眼用膜或眼用膜。过渡金属配合物的一部分,或其混合物。 2.根据权利要求1的制剂,其特征在于在溶液中具有官能团的胺基过渡金属的盐或络合物的浓度为0.15-7.0重量%。 3.根据权利要求1的制剂,其特征在于,使用蒸馏水或等渗溶液或其混合物作为溶液的水性介质。 4.根据权利要求3所述的制剂,其特征在于,选择BBS的生理或平衡生理溶液和/或非离子化合物的水溶液,例如甘油,山梨糖醇,中药,或丙二醇或葡萄糖,作为等渗溶液。 。 2.根据权利要求1所述的药物,其特征在于,所述水溶液还包含胶凝剂。 6.根据权利要求5的制剂,其特征在于所用的胶凝剂是透明质酸,硫酸软骨素或聚乙烯醇,或甲基纤维素,或羟乙基纤维素,或羟丙基纤维素,或羟丙基瓜尔胶,或聚乙二醇-聚丙二醇-聚乙二醇。纤维素共聚物,聚乙二醇纤维素,交联聚丙烯酸的盐及其与丙烯酸C10-30烷基酯的共聚物,或它们的混合物。 7.根据权利要求5和6的制剂,其特征在于,所述胶凝剂在水溶液中的含量为0.1-25.0重量%。 8.毒品

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