METHODS AND APPLICATION OF EX VIVO FABRIC CULTURE SYSTEMS

摘要

1. A method of maintaining tissue ex vivo, comprising: implanting an implantable device in a subject, whereby the implantable device is populated by at least one of the stem cells, differentiated cells and diseased cells; extracting the implantable device and tissue contained in the implanted device from the subject; providing perfusion of fluid to the tissue. 2. The method according to claim 1, further comprising the step of extracting tissue from the implantable device to ensure fluid perfusion. The method of claim 2, further comprising the step of placing the tissue in the microfluidic system until the fluid is perfused. The method according to any one of paragraphs. 1-3, characterized in that the implantable device includes at least one cell growth chamber and at least one open port, allowing passage to the cell growth chamber to allow cells to enter the cell growth chamber for population by cells. . The method according to claim 1, characterized in that the implantable device is a microfluidic device. The method of claim 5, further comprising attaching a microfluidic device to the microfluidic system. The method according to any one of paragraphs. 5 and 6, characterized in that the microfluidic device includes at least one cell growth chamber and at least one open port, allowing passage to the cell growth chamber to allow cells to enter the cell growth chamber for population by cells. . The method according to any one of paragraphs. 5 and 6, characterized in that the microfluidic device includes at least one fluid channel, separated from at least one