DRY COATED TABLET CONTAINING TEGAFUR, HIMERACYL AND POTASSIUM OTERACIL
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机译:含有替加氟,庚酰基和钾钾微晶的干包衣片剂
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摘要
1. A dry-coated tablet containing: an inner core containing (a) tegafur, (b) gimeracil and (c) potassium otracil, and the outer shell as active ingredients. The dry-coated tablet according to claim 1, which contains (a) tegafur, (b) gimeracil and (c) potassium otracil in a molar ratio of 1: 0.4: 1.3. A dry-coated tablet according to claim 1 or 2, wherein the active ingredients, consisting of (a) tegafur, (b) gimeracil and (c) potassium otracil, comprise from 50% wt. up to 100% wt. by mass of the components of the inner core. 4. The dry-coated tablet according to claim 1, wherein the active ingredients, consisting of (a) tegafur, (b) gimeracil and (c) potassium otracil, comprise from 70% wt. up to 99% wt. by mass of the components of the inner core. 5. A dry-coated tablet according to claim 1, wherein the total content of active ingredients (a) to (c) is from 10 to 60% by weight. by weight of the dry-coated tablet. 6. A dry-coated tablet according to claim 1, wherein the outer shell contains one, two or three compounds of lactose, crystalline cellulose and hydroxypropyl cellulose. The dry-coated tablet of claim 6, wherein the outer shell contains one or two compounds of lactose and crystalline cellulose. The dry-coated tablet of claim 7, wherein the outer shell contains lactose and crystalline cellulose. A dry-coated tablet according to claim 6, 7 or 8, wherein the outer shell further comprises a disintegrant. 10. The dry-coated tablet of claim 9, wherein the disintegrant is selected from the group consisting of crospovidone, carmellose, corn starch, low substitution hydroxypropyl cellulose and partially pregelatinized starch. 11. Covers�
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