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METHOD FOR PREDICTION OF EARLY COMPLICATIONS FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY

机译:冠状动脉搭桥术后早期并发症的预测方法

摘要

FIELD: medicine.;SUBSTANCE: invention can be used for the purpose of predicting early postoperative (for the first 6 postoperative days) complications in the form of organ dysfunctions in the patients following coronary artery bypass graft surgery. To this effect, within 25-35 minutes upon the beginning of the bypass procedure, the following central haemodynamics values are measured: blood pressure (BP) and central venous pressure (CVP), homeostasis including the blood lactate concentration (Lact), oxygen partial pressure in venous (pvO2) and arterial blood (paO2), and the packed cell volume (Ht). Besides, the time of the bypass (t1), the time of the aortic compression (t2) and the patient's age are determined, and a discriminator is derived by formula: D=3.321+(0.006)*AP+(0.011)*CVP+(1.030)*Lact+(-0.009)*paO2+(0.005)*pvO2+(-0.124)*Ht+(-0.023)*age+(0.014)*t1+(-0.019)*t2. If D-0.6, the low risk of early postoperative organ dysfunctions is stated. The values D0.6 enable stating the high risk of the organ dysfunctions. The value falling within the range of -0.6D0.6 provides characterising an uncertainty interval, and if the derived value D falls within the range, the patient's state is monitored including more frequent measurement of the standard parameters.;EFFECT: more rapid achievement of the prediction results with maintaining the high prediction accuracy, availability of the results during the bypass graft surgery directly, once the bypass procedure has been completed.;2 tbl, 4 dwg, 2 ex
机译:领域:药物:本发明可用于以冠状动脉搭桥手术后的患者的器官功能障碍的形式预测术后早期(术后的前6天)并发症的目的。为此,在旁路手术开始后的25-35分钟内,测量以下中央血液动力学值:血压(BP)和中央静脉压(CVP),包括血液乳酸浓度(Lact)在内的体内平衡,氧分静脉血(pvO2)和动脉血(paO2)的压力以及细胞的堆积体积(Ht)。此外,确定旁路时间(t1),主动脉受压时间(t2)和患者的年龄,并通过以下公式得出鉴别器:D = 3.321 +(0.006)* AP +(0.011)* CVP +( 1.030)* Lact +(-0.009)* paO2 +(0.005)* pvO2 +(-0.124)* Ht +(-0.023)*年龄+(0.014)* t1 +(-0.019)* t2。如果D <-0.6,则表明术后早期器官功能障碍的风险较低。值D> 0.6可以说明器官功能障碍的高风险。落在-0.6

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