METHOD OF ESTIMATING IMPAIRMENT OF MICROVISCOSITY OF MEMBRANES OF PERIPHERAL BLOOD ERYTHROCYTES IN PREGNANT WOMEN IN THIRD TRIMESTER OF GESTATION IN CASE OF CYTOMEGALOVIRUS INFECTION AGGRAVATION

摘要

FIELD: medicine.;SUBSTANCE: invention relates to field of medicine and can be used to estimate stability of membranes of peripheral blood erythrocytes in pregnant women with cytomegalovirus infection in the third trimester of gestation. Method is characterised by the following: titre of antibodies to cytomegalovirus, eximerisation factor in lipid bilayer and in protein-lipid layer are determined, microviscosity in membranes of erythrocytes is estimated and activity of adenosine triphosphate in erythrocytes is determined. If titre of antibodies to cyclomegalovirus is 1:1600, activity of adenosine triphosphate reduces to 0.40±0.008 mcmol/ml, microviscosity in membranes of erythrocytes is impaired, eximerisation factor in lipid bilayer reduces to 0.59±0.006 Fe/Fm, and in protein-lipid layer - to 0.70±0.004 Fe/Fm, threat to stability of membranes of erythrocytes is estimated.;EFFECT: estimation of stability of membranes of erythrocytes in peripheral blood in pregnant women with cytomegalovirus infection in the third trimester of gestation.