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METHOD OF TREATING PATIENT WITH HYPERTROPHIC CARDIOMYOPATHY

机译:治疗肥厚性心肌病的方法

摘要

FIELD: medicine.;SUBSTANCE: method involves recovering DNA, detecting polymorphism of AGTR1 gene coding angiotensin II receptor type 1. That is followed by detecting polymorphism of ACE gene coding angiotensin converting enzyme; in case of having combinations of AC(AGTR1)/ID(ACE) or AA(AGTR1)/DD(ACE) genotypes detected, angiotensin II receptor blockers, in particular losartan 50mg twice a day are prescribed as a part of the complex therapy.;EFFECT: invention enables developing the treatment procedure involving the angiotensin II receptor blockers taking into account its genetic traits for increasing the therapeutic effectiveness of both nonobstructive, and obstructive forms of hypertrophic cardiomyopathy.;3 tbl, 2 ex
机译:领域:方法:方法包括回收DNA,检测编码1型血管紧张素II受体的AGTR1基因的多态性,然后检测编码血管紧张素转化酶的ACE基因的多态性;如果检测到AC(AGTR1)/ ID(ACE)或AA(AGTR1)/ DD(ACE)基因型的组合,则将血管紧张素II受体阻滞剂(尤其是每天50 mg的氯沙坦)作为两次复杂治疗的一部分。效果:本发明能够开发涉及血管紧张素II受体阻滞剂的治疗方法,并考虑到其遗传特性,以提高非阻塞性和阻塞性肥厚型心肌病的疗效。3 tbl,2 ex

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