APPLICATION OF PHARMACEUTICAL COMPOSITION, BASED ON SALT OF QURTERNARY PHOSPHONIUM AND SUBSTITUTED DINITROBENZOFUROXANE FOR TREATMENT OF PIROPLASMOSIS IN DOGS AND TREATMENT METHOD

摘要

FIELD: medicine.;SUBSTANCE: invention relates to veterinary, namely to parasitology. Application of a pharmaceutical composition, containing n-tetradecyltri-n-butylphosphonium chloride and 5,7-bis-(m-nitroanilino)-4,6-nitrobenzofuroxane as active components with their weight ratio of 1:10 and glucose as an auxiliary substance, as an anti-piroplasmosis medication for the treatment of dogs. The said anti-piroplasmosis medication is introduced orally two times with a 24 hour interval in a dose of 350 mg/kg of live weight. The anti-piroplasmosis medication possesses high anti-parasitic activity and low toxicity (LD50 2500 mg/kg).;EFFECT: invention provides an increase of treatment efficiency.;2 cl, 2 dwg, 2 tbl, 1 ex