METHOD FOR THERMAL CHEMORADIATION OF ADVANCED NON-SMALL CELL LUNG CANCER

摘要

FIELD: medicine.;SUBSTANCE: there are involved local hyperthermia, teletherapy and chemotherapy. The chemotherapy is two-staged and follows the schedule: paclitaxel 175 mg/m² intravenously drop-by-drop for 3 hours and carboplatin AUC 6 intravenously drop-by-drop on the 1^st and 22^nd days. The teletherapy starts from the 3rd day in the multi-fractionation mode for 5 weeks in a dose of 1.3 Gy × 2 times a day to reach a total boost dose of 66 isoGy. The hyperthermia is conducted from the 1^st to 33^rd days of the chemotherapy 3 times a day, 15 sessions in all, 3 hours before administering the chemopreparations or conducting the radiation session to temperature 42 to 44°C for 60 min.;EFFECT: higher patient's survival rate ensured by reducing incidence of local recurrences and remotes metastases accompanied by improving acceptability of the treatment and quality of life.;1 ex