OPHTHALMIC COMPOSITIONS WITH POLY(ETHYLENE OXIDE)-POLY(BUTYLENE OXIDE) BLOCK COPOLYMERS

摘要

FIELD: medicine.;SUBSTANCE: group of inventions refers to medicine, namely to ophthalmology, and aims at treating dry eye syndrome, for contact lens disinfection and remoistening. A sterile water-based ophthalmic composition contains poly(ethylene oxide)-poly(butylene oxide) block copolymer of formula (EO)_m(BO)_n and galactomannan. Herewith, m has an average value of 45, and n has an average value of 9 to 18. Said galactomannan represents guar or its derivative. Besides, presented are a method for treating dry eye syndrome and a method for disinfecting a contact lens with using the above composition. The other embodiment discloses a method for delivering a pharmaceutical agent into the eyes involving the local administration of a formulation containing one or more pharmaceutically active agents and the above composition into the eyes.;EFFECT: using the group of inventions enables ensuring the more effective application of the above composition by providing the additional stability of a lachrymal film of the composition.;19 cl, 6 tbl, 29 dwg, 3 ex