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METHOD FOR INDUCING DEATH OF PLURIPOTENT STEM CELLS AND DIFFERENTIATED CELLS DIFFERENT FROM CARDIOMYOCYTES

机译:诱导来自心肌细胞的多能干细胞和分化细胞死亡的方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to biotechnology. What is presented is a method for inducing the death of pluripotent stem cells and cells different from cardiomyocytes originated from the pluripotent stem cells, in the culture in vitro, by culturing a cell population containing the pluripotent stem cells, the cells different from cardiomyocytes originated from the pluripotent stem cells, and the cardiomyocytes originated from the pluripotent stem cells, in a hypertonic solution containing saccharides (carbohydrate) and having the osmotic pressure from 370 mosmole/kg to 1000 mosmole/kg.;EFFECT: method enables purifying the cardiomyocytes from the pluripotent stem cells keeping the cardiomyocytes alive.;8 cl, 15 dwg, 2 tbl, 11 ex
机译:领域:医学。;物质:发明是指生物技术。提出了一种在体外培养中通过培养包含多能干细胞的细胞群来诱导多能干细胞和不同于多能干细胞的心肌细胞死亡的细胞的方法,所述多能干细胞不同于源自于心肌细胞的细胞。多能干细胞和源自多能干细胞的心肌细胞在含有糖类(碳水化合物)且渗透压为370 mosmole / kg至1000 mosmole / kg的高渗溶液中; EFFECT:该方法可从中纯化心肌细胞多能干细胞使心肌细胞保持活力; 8 cl,15 dwg,2 tbl,11 ex

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