METHOD FOR ASSESSING ENDOMETRIAL CANCER PROGRESSION IN PATIENTS WITH HYPERPLASTIC PROCESSES IN ENDOMETRIUM

摘要

FIELD: medicine.;SUBSTANCE: clinical anamnestic parameters are determined in the patients with hyperplastic processes in the endometrium, and a hysteroscopy with an endometrial biopsy is performed. The activity of calpains, total activity of proteasomes, and activity of 20S proteasomes are determined. Age-dependent discriminator functions Y1 and Y2 are determined by formulas. If Y1Y2, the patient is referred to a group of low risk of endometrial cancer development. If Y1Y2, the patient is referred to a group of high risk of endometrial cancer development.;EFFECT: invention enables the high-sensitivity and specificity prediction of endometrial cancer development in the patients suffering from the hyperplastic processes in the endometrium.;1 tbl, 3 ex