首页> 外国专利> Acethylcholine esterase inhibitors as a means of reducing the effects of increased stress or its prevention - in iatrogenic Cushing's syndrome and others, i.a. HPA-mediated undesirable effects in high-dose, long-lasting gluto

Acethylcholine esterase inhibitors as a means of reducing the effects of increased stress or its prevention - in iatrogenic Cushing's syndrome and others, i.a. HPA-mediated undesirable effects in high-dose, long-lasting gluto

机译:乙酰胆碱酯酶抑制剂可作为减轻医源性库欣氏综合症和其他疾病的一种手段,以减轻压力增加或预防压力增加。 HPA介导的大剂量,持久谷氨酸不良反应

摘要

Use of acetylcholinesterase inhibitors as a medication, characterized by new, previously unknown effects for the reduction and prevention of stress-related symptoms / disorders of iatrogenic and / or bio-psycho-social aetiology: 1. as a medication with new, previously unknown effects in glucocorticoid therapy, 1.1. characterized by the reduction and prevention of the following undesirable effects in the initial phase of glucocorticoid therapy 1.1.1. seizure-related tachycardia, 1.1.2. Arrhythmia, 1.1.3. pectanginal seizures, 1.1.4. elevated blood pressure, 1.1.5. Lifting and dizzy spells, 1.1.6. eerie feelings in the head and chest, 1.1.7. Heat and sweat attacks, 1.1.8. Polypnea, 1.1.9. Visual disturbances that may be associated with dilated pupils, 1.1.10. occasionally photopsies, 1.1.11. sounding noises, 1.1.12. Constipation, 1.1.13. Sleep Disorders, 1.1.14. Tremor, 1.1.15. inner unrest; 1.2. characterized by the reduction and prevention of iatrogenic Cushing syndrome with 1.2.1. Moon Face, Buffalo Neck, 1.2.2. Hypertension, 1.2.3. Diabetes mellitus, 1.2.4. Obesity strain, 1.2.5. sec. Amenorrhoea, 1.2.6. Growth disorders in childhood; 1.3. characterized by the amelioration of the following diseases resulting from glucocorticoid therapy: 1.3.1. Osteoporosis, 1.3.2. Glaucoma; 2. as a medication with new, previously unknown effects, characterized by the reduction / elimination of stress-related symptoms in psychiatric, psychosomatic and / or psycho-social disorders: 2.1. Anxiety disorders and phobias 2.1.1. Panic Disorders 2.1.2. Fear of heights 2.1.3. Claustrophobia 2.1.4. Test anxiety 2.1.5. social anxiety 2.2. depressive disorders, 2.3. Burnout, 2.4. Stress disorders, 2.5. Adjustment disorders, 2.6. sympathicotonic sleep disorders, 2.7. ADHD; 3. as a medication with new, previously unknown effects, characterized by the significant reduction / elimination of central sympathetic excitation with corresponding symptoms in: 3.1. Borderline hypertension, 3.2. severe, long or chronic diseases; 4. A method for achieving the effect according to claims 1 to 3, characterized in that the intake of an acetylcholinesterase inhibitor takes place half an hour before meals and at bedtime and additional income when needed are possible.
机译:乙酰胆碱酯酶抑制剂作为药物的用途,其特征在于减轻和预防与压力有关的症状,医源性和/或生物心理社会病因的新的,以前未知的作用:1.作为具有新的,以前未知的作用的药物在糖皮质激素治疗中,1.1。其特征在于在糖皮质激素治疗1.1.1的初期减少和预防以下不良影响。癫痫发作相关的心动过速,1.1.2。心律失常,1.1.3。胸膜惊厥1.1.4。血压升高1.1.5。令人目眩神迷的咒语1.1.6。 1.1.7的头部和胸部怪异的感觉。 1.1.8。息肉1.1.9。 1.1.10。可能与散瞳有关的视觉障碍。偶尔进行活检,1.1.11。声音1.1.12。便秘1.1.13。睡眠障碍,1.1.14。震颤,1.1.15。内乱1.2。 1.2.1可以减少和预防医源性库欣综合征。月圆脸,水牛颈,1.2.2。高血压1.2.3。糖尿病1.2.4。肥胖应变1.2.5。秒闭经1.2.6。儿童时期的生长障碍; 1.3。其特征在于改善了糖皮质激素治疗引起的以下疾病:1.3.1。骨质疏松症1.3.2。青光眼; 2.作为一种具有新的,以前未知的作用的药物,其特征在于减少/消除了精神病,心身病和/或社会心理疾病中与压力有关的症状:2.1。焦虑症和恐惧症2.1.1。恐慌症2.1.2。对高度的恐惧2.1.3。幽闭恐惧症2.1.4。测试焦虑2.1.5。社交焦虑2.2。抑郁症,2.3。倦怠,2.4。压力障碍2.5。调整障碍,2.6。交感神经睡眠障碍,2.7。多动症; 3.作为具有新的,以前未知的作用的药物,其特征在于明显减少/消除了中央交感神经兴奋,并具有以下相应的症状:3.1。临界高血压3.2。严重,长期或慢性疾病; 4.根据权利要求1至3所述的达到效果的方法,其特征在于,乙酰胆碱酯酶抑制剂的摄入发生在进餐前半小时和就寝时间,并且在需要时可以增加收入。

著录项

  • 公开/公告号DE102013011397A1

    专利类型

  • 公开/公告日2015-01-08

    原文格式PDF

  • 申请/专利权人 ANNETTE SCHUBERT;BRIGITTE VÖLZ;

    申请/专利号DE20131011397

  • 发明设计人 BRIGITTE VÖLZ;ANNETTE SCHUBERT;

    申请日2013-07-08

  • 分类号A61K45;A61P5/46;A61P25;

  • 国家 DE

  • 入库时间 2022-08-21 14:55:47

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