new compounds of carbon dioxide - mineral salt type i and ii of the procains and derived analogues, their production and stabilization method for targeted local and systemic pharmaceutical applications

摘要

the subject of this patent application are new compounds of carbon dioxide - mineral salt type of procains and derived stable analogues as cyclic polymers (oil and trimere) of type i and in dilute solution by kohlensu00e4urezusatz stabilized monomerer type iiwhat (= hydrogen or deuterium to understand and x = f, cl, br or h meansprocedures to arzneimittelgerechten manufacture as mediators for human and veterinary pharmaceutical applications, local and systemic, the actual substance, some procaine or some procainanaloga under physiologically adapted on-site conditions without prior metabolism to de a target transport.the erfindungsgemu00e4u00dfen compounds have the ability to barriers such as the skin, intestine and cell membranes to happen and their pharmaceutical effect than pain, anti-inflammatory and immunomodulatory agents with good tolerance in systemic and local applications to unfold. the physiological adaptation of the active substance and carbon dioxide - procain orprocainanaloges base pair is a significant wirkstoffeinsparung allows, not least by the carrierwirkung of carbonic acid and its salts is guaranteed.11medicine, neuraltherapeuten, enzymatic fission productsthrough the use of a new substance specific approach, a new way, a narrow path for the stable and metastable molecules to identify, to their production, which has not yet been possible to ensure the was. it was working with a surplus.2and a defined amount of water (carbonated water) and the presence of a mineralsalzes as nacl, through which the reaktionsgleichgewicht significantly in favour of the target products could be drawn. the main reasons for this specific reaction is the fact that a surplus.2in both concentrated and diluted medication a drift in the acid range without decomposition of the hydrogencarbonats allows. this is on the one hand, for compounds of type i and type ii are used.from the solid type i may be located using dilute carbonic acid injection and infusion solutions of type ii for the effective, more effective and acceptable. carbon dioxide - salts of type i and type ii are equally excellent.