NON-CONSERVATIVE PHARMACEUTICAL COMPOSITIONS FOR OPHTHALMIC ADMINISTRATION

摘要

Ophthalmic product which is container with integrated bacterial protection system and dispensing tip is claimed. The ratio of inner and outer diameter of tip is 1:1-1:6. The container comprises ophthalmic composition discharged from tip into eye of patient, where the composition is a preservative-free aqueous solution and contains excipients so that viscosity is less than 200 cP at 25[deg] C, surface tension is less than 22 mN/m and more than 10 mN/m at 25[deg] C, and the dispensing tip and properties of composition in combination discharges drops of volume of 22-31 mu l when the tip is at 45[deg] .