COMPOUND FOR INHIBITING ACTIVITY OF GLUTATHIONE S-TRANSFERASE OMEGA 1 AND PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUND

摘要

The present invention relates to a compound for inhibiting the activity of Glutathione s-transferase omega 1 and pharmaceutical compositions thereof. The present invention also relates to a method for preparing the above-mentioned compound. The compound for inhibiting the activity of Glutathione s-transferase omega 1 in the present invention has a structure as shown by the following general formula (I), wherein the cycle A is a para-hydroquinone alcohol ring, R is selected from the group consisting of the following general formula (Ia) and general formula (Ib), and n of general formula (Ia) is 1 or 2, m of general formula (Ib) is 0 or 1, R¹ is H or ArCH₂^-, and R² is Alkyl^- or Alkyl^-.