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TREATMENT OF ALZHEIMER'S AND COGNITIVE IMPAIRMENT WITH ANDROGRAPHOLIDES
TREATMENT OF ALZHEIMER'S AND COGNITIVE IMPAIRMENT WITH ANDROGRAPHOLIDES
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机译:雄激素类药物治疗老年痴呆症和认知障碍
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摘要
We found that Andrographolide binds to GSK-3: In so doing, andrographolide prevents changes in neuropathology in an Alzheimer's model, reducing Amyloid- peptide levels, changing the ontogeny of hippocampus and cortex amyloid plaques, and reducing tau phosphorylation around Amyloid-. Andrographolide recovers spatial memory functions in an Alzheimer's model. Andrographolide and its derivatives may be used to treat Alzheimer's disease.
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