METHOD FOR PRODUCING ANTIBACTERIAL POLYMETHYL METHACRYLATE BONE CEMENT POWDER AND ANTIBACTERIAL POLYMETHYL METHACRYLATE BONE CEMENT POWDER

摘要

PROBLEM TO BE SOLVED: To provide a method suitable for the production of a freely flowing antibacterial bone cement powder containing fosfomycin and having flowability.SOLUTION: The method for producing an antibacterial bone cement powder comprises mixing a bone cement raw material powder having a water content of 1.0 wt% or less with tromethamol-fosfomycin to form a bone cement powder in a step A and drying the bone cement powder until the water content attains 1.0 wt% or less in a step X. The bone cement raw material powder is a polymer powder and the polymer is selected from a poly(methacrylic acid methyl ester), a poly(methacrylic acid ethyl ester), a poly(methylmethacrylic acid propyl ester), a poly(methacrylic acid isopropyl ester), a poly(methyl-methacrylate-co-methylacrylate), a poly(styrene-co-methylmethacrylate) and a mixture of at least two of theses polymers.SELECTED DRAWING: None