首页> 外国专利> METHOD OF MEASURING INTENSITY OF HANGOVER, METHOD OF INDUCING HANGOVER OF TEST ANIMALS, METHOD OF MEASURING HANGOVER SYMPTOM RESTRAINING EFFECT, METHOD OF SCREENING HANGOVER RESTRAINING DRUG, AND METHOD OF SELECTING ALCOHOLIC DRINK LESS LIKELY TO INDUCE HANGOVER

METHOD OF MEASURING INTENSITY OF HANGOVER, METHOD OF INDUCING HANGOVER OF TEST ANIMALS, METHOD OF MEASURING HANGOVER SYMPTOM RESTRAINING EFFECT, METHOD OF SCREENING HANGOVER RESTRAINING DRUG, AND METHOD OF SELECTING ALCOHOLIC DRINK LESS LIKELY TO INDUCE HANGOVER

机译:宿醉强度的测量方法,引起试验动物宿醉的方法,宿醉症状抑制作用的测量方法,宿醉抑制药物的筛选方法以及选择酒精性饮料的方法,可避免宿醉

摘要

PROBLEM TO BE SOLVED: To provide a method of quantitatively (objectively) measuring the intensity of hangover, a method of inducing hangover on test animals, a method of measuring potency of hangover restraining drugs, a method of screening hangover restraining drug, and a method of selecting alcoholic drink less likely to induce hangover.SOLUTION: A method of measuring the level of hangover comprises: (A) a step of administering ethanol to test animals and then reducing to substantial zero the alcohol concentrations in the blood of the animals in an active period; (B) a step of inducing a state of hangover on the animals in the active period by, after the administration of ethanol, substantially reducing the quantity of actions and/or spontaneous exercise quantity of the test animals; and (C) a step of measuring the quantity of actions and/or spontaneous exercise quantity of the test animals since the start of the active period.
机译:解决的问题:提供一种定量(客观地)测量宿醉强度的方法,一种在测试动物上诱发宿醉的方法,一种测量宿醉抑制药效价的方法,一种筛选宿醉抑制药的方法以及一种方法。解决方案:测量宿醉水平的方法包括:(A)给予乙醇以测试动物的步骤,然后将动物血液中酒精浓度降低到基本为零。活动期; (B)通过在施用乙醇后,显着减少试验动物的动作量和/或自发运动量,在活动期中引起动物宿醉状态的步骤; (C)测量自活动期开始以来测试动物的动作量和/或自发运动量的步骤。

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