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Novel immunotherapy for several types of tumors such as lung cancer including NSCLC

机译:针对包括NSCLC在内的多种类型肿瘤(例如肺癌)的新型免疫疗法

摘要

The present invention relates to peptides, nucleic acids, and cells for use in immunotherapy. In particular, the present invention relates to cancer immunotherapy. The present invention relates to a tumor-associated cytotoxic T cell (CTL) peptide epitope that acts as an active pharmaceutical ingredient of a vaccine composition that stimulates an anti-tumor immune response, alone or in combination with other tumor-related peptides. Further on. The present invention provides more than 70 novel peptide sequences derived from HLA class I and HLA class II molecules of human tumor cells that can be used in vaccine compositions to elicit anti-tumor immune responses, and variants thereof About.
机译:本发明涉及用于免疫疗法的肽,核酸和细胞。特别地,本发明涉及癌症免疫疗法。本发明涉及肿瘤相关的细胞毒性T细胞(CTL)肽表位,其单独或与其他肿瘤相关肽一起用作刺激抗肿瘤免疫应答的疫苗组合物的活性药物成分。进一步。本发明提供了超过70种衍生自人肿瘤细胞的HLA I类和HLA II类分子的新颖肽序列,其可用于疫苗组合物中以引发抗肿瘤免疫应答,及其变体。

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