METHOD FOR PRODUCING COMPOUND HAVING 1,2-AMINO ALCOHOL SKELETON

摘要

PROBLEM TO BE SOLVED: To provide a method for producing 1,2-amino alcohols that has a high regioselectivity and is safe and efficient.;SOLUTION: Provided is a method for producing 1,2-amino alcohols represented by formula 3 below by letting an electrophilic nitrogenation reagent 1-amino pyridinium derivative exemplified by formula 1a below act, under the irradiation of light, on alkene represented by formula 2 below, under the presence of a photocatalyst such as tris(2-phenyl pyridine)iridium. [R¹, R², and R³ are each H, a C1 to 5 alkyl group, a phenyl group, a substituted phenyl group, a methoxycarbonyl group, an ethoxycarbonyl group, a phenoxy carbonyl group, or a benzyloxycarbonyl group; R¹ and R², or R¹ and R³ may bond to each other to form a ring.].;SELECTED DRAWING: None;COPYRIGHT: (C)2016,JPO&INPIT