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Protein crystallization conditions search agent and protein crystallization conditions search method

机译:蛋白质结晶条件检索剂及蛋白质结晶条件检索方法

摘要

{Problems} To provide an agent that is used for searching protein crystallization conditions, and has improved properties of promoting protein crystal formation and improved operability, and a method for searching for protein crystallization conditions using the same. {Means to solve} An agent for searching for protein crystallization conditions, containing a water-swellable layered silicate having a fluorine atom and a hydroxyl group, wherein the fluorine atom is covalently bonded to the silicate by isomorphous substitution with the hydroxyl group. A method of searching for protein crystallization conditions, which comprises a step of mixing the agent for searching for protein crystallization conditions described above and a solution in which a protein is dissolved.
机译:发明内容提供一种用于寻找蛋白质结晶条件并具有促进蛋白质晶体形成的性质和改善的可操作性的试剂,以及使用该试剂来寻找蛋白质结晶条件的方法。 {解决的手段}一种用于寻找蛋白质结晶条件的试剂,其包含具有氟原子和羟基的水溶胀性层状硅酸盐,其中所述氟原子通过与羟基的同构取代而共价键合至所述硅酸盐。一种寻找蛋白质结晶条件的方法,该方法包括将上述用于寻找蛋白质结晶条件的试剂与溶解了蛋白质的溶液混合的步骤。

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