S-nitroso-N-acetylpenicillamine (SNAP) doped thrombus-resistant / bactericidal nitric oxide releasing polymer with improved stability

摘要

SOLUTION: A polymer film is a separated S-nitrosothiol adduct or polymer S-nitrosothiol associated with the polymer matrix by covalent bonding to the polymer matrix; dispersion within the polymer matrix; or both. Including a polymer matrix having at least one of the adducts, the separated S-nitrosothiol adduct or at least one of the polymer S-nitrosothiol adducts releasing nitric oxide (NO). Is possible. The polymer matrix is a polyurethane polymer matrix, a silicone rubber polymer matrix, or a copolymer matrix of polyurethane and silicone rubber. [Selection] Figure 1B