Monosaccharide phosphoric acid or surface-modified hydrophilic nanoparticles in its derivatives, the colloidal solution and its applications

摘要

The present invention , hydrophilic nanoparticle composition monosaccharide phosphoric acid or a derivative thereof is attached to the surface , a colloidal solution of the composition is dispersed in water , and a magnetic resonance imaging contrast agent containing the colloidal solution . In accordance with the present invention , it is possible to modify the surface of the inorganic nanoparticles , it is possible to produce nanoparticles having a biocompatible and excellent water- dispersibility. Nanoparticles produced in this way , biometric image areas such as magnetic resonance imaging contrast agents , nanoparticles , such as quantum dot light emitting devices - electronic fusion art efficiently in a variety of fields, including biomedical fields such as hyperthermia it can be used . Also , compared to nano- particles dispersed by conventional dispersion stabilizer and has a dynamic size excellent dispersion stability and relatively small fluid . [ Selection Figure ] Figure 3