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Five-membered and six-membered heterocyclic compound and method for producing the same, pharmaceutical composition and use thereof

机译:五元和六元杂环化合物及其制备方法,药物组合物和用途

摘要

In the present invention, the 5-membered and 6-membered heterocyclic compounds represented by Formula I are used as pharmacologically recognized salts, metabolites, metabolites, or original drugs, and their production methods, drug combinations Information on things and applications is made public. The 5-membered and 6-membered heterocyclic compound of the present invention has activity as a Janus kinase (JAK) inhibitor and can also treat diseases caused by abnormal kinase activity. For example, it is used for the production of diseases for cell proliferation such as cancer or drugs for treating these diseases.
机译:在本发明中,由式I表示的5元和6元杂环化合物被用作药理学上认可的盐,代谢物,代谢物或原始药物,并且它们的制备方法,药物组合物和用途的信息被公开。本发明的5元和6元杂环化合物具有作为Janus激酶(JAK)抑制剂的活性,并且还可以治疗由异常激酶活性引起的疾病。例如,它用于产生细胞增殖性疾病,例如癌症或用于治疗这些疾病的药物。

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