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Compositions and methods for treating and preventing cancer by targeting tumor-associated carbohydrate antigens

机译:通过靶向肿瘤相关碳水化合物抗原来治疗和预防癌症的组合物和方法

摘要

Disclosed are compositions useful for eliciting an anti-TACA immune response, as well as kits containing the same, and methods of using the compositions to treat and prevent cancer. Disclosed is an isolated human antibody that binds to a glycomimetic peptide, as well as a method of making the same, and its use to treat and prevent cancer. Disclosed is an isolated human NK cell useful for killing tumor cells, as well as an isolated human dendritic cell, and methods for making it, and its use for treating and preventing cancer. [Selection] Figure 13
机译:公开了可用于引发抗TACA免疫应答的组合物,以及包含该组合物的试剂盒,以及使用该组合物治疗和预防癌症的方法。公开了一种与拟糖肽结合的分离的人抗体,及其制备方法,及其在治疗和预防癌症中的用途。公开了可用于杀死肿瘤细胞的分离的人NK细胞,以及分离的人树突状细胞,及其制备方法,以及其在治疗和预防癌症中的用途。 [选择]图13

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