Method for quantitatively detecting 8-oxo-2'-deoxyguanosine in an aqueous sample solution with high sensitivity

摘要

There is provided a method for quantitatively detecting 8-oxo 2'-deoxyguanosine in an aqueous sample solution with high sensitivity. A method for quantitatively detecting 8-oxo 2'-deoxyguanosine in an aqueous sample solution, comprising the steps of 1) immobilizing a fluorescent probe molecule showing a fluorescence response specific to 8-oxo 2'-deoxyguanosine on surfaces of fine particles via a spacer unit and bringing the sample solution into contact with the fine particles, and 2) measuring a physical property of the fine particles before and after the contact with the sample solution to determine a change in the physical property.