Kondeyuramin F-4 derivative, acid addition salts and methods for their preparation to inhibit glycosidase

摘要

PROBLEM TO BE SOLVED: To provide a new conduramine F-4 derivative or its acid-added salt useful as a highly active glycosidase inhibitor, and to provide a method for producing the same.;SOLUTION: A conduramine F-4 derivative or its acid-added salt is represented by general formula (1) or (2), wherein R₁ and R₂ are each H, alkyl, hydroxyalkyl, alkenyl, alkynyl, acyl, aryl, heteroaryl or aralkyl; R₁ and R₂ may form a nonaromatic ring by combining with the nitrogen atoms binding thereto respectively; R₁ and R₂ are not H at the same time; R₃ to R₅ are each hydroxy or protected hydroxy; R₄ and R₅ may form an acetal group by combining together; and R₆ is H or methyl.;COPYRIGHT: (C)2014,JPO&INPIT